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Lastly, research has shown that utilizing an M2-targeting peptide-modified liposome carrier for YY1-targeted therapy in M2 macrophages is highly effective in inhibiting PCa cell lung metastasis and exhibits synergistic antitumor effects when combined with PD-1 blockade (Chen et al., 2023)
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The experiment started when mice were 4 months of age and ended when they were 7 months of age for a treatment period of three months (12 weeks)
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