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Gestational Hypoxia and Blood-Brain Barrier Permeability: Early Origins of Cerebrovascular Dysfunction Induced by Epigenetic Mechanisms - Frontiers

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While the specific roles and interactions of direct viral mechanisms, indirect effects mediated by the host immune response, and these other contributing factors in NeuroHIV pathogenesis remain complex and not fully elucidated, growing evidence increasingly highlights the central role of microglial activation and subsequent neuroinflammation