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Monitoring Parameters When Co-Prescribing Clinical Signs to Track Patients co-using GHK-Cu and pregabalin should be evaluated at each visit for: Excess somnolence or sedation beyond what pregabalin alone produces at baseline Dizziness, ataxia, or balance disturbance Cognitive slowing or memory complaints new to the combination period Skin or injection-site reactions (specific to subcutaneous GHK-Cu) Pregabalin does not have a standard therapeutic drug monitoring serum assay used in outpatient practice, so monitoring is clinical rather than laboratory-based for most patients [4]
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