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Regardless, once formed, a protein sulfenate would rapidly react with GSH to produce the mixed disulfide, and this could be the mechanism through which PSSG formed for some proteins in the cytosol during oxidative stress when H 2 O 2 is high enough to overcome a slow rate constant
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Potency:50 mg
21 , 22 Its activation may reflect PLCγ-mediated production of diacylglycerol (which in turn promotes PKC activity), and PI3K-mediated activation of Rac, likely via Bruton’s tyrosine kinase (BTK)
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