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Desrinal 5 mg Tablet 20 Pieces Anti-Aging Cream And Serum If you still have aProduct Description. Desloratadine is an antihistamine. It is used to relieve the symptoms of hay fever and hives of the skin. Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Dosage. Adults and adolescents (12 years of age and over). The recommended dose of desrinal is one tablet once a day. Side effects. headache. nausea.