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Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2’-amino-N- (3,4-dimethyl-5-isoxazolyl)-4’-(2-methylpropyl)[1, 1’-biphenyl]-2-sulfonamide (BMS-187308) J Med Chem
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