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glutathione for ocd N-acetylcysteine: An Innovative Approach to... : Advances in Human Biology Capsules:120 Capsules Herbal Medicine Metabolic Parkinson's disease -
Metabolic Parkinson's disease - Frontiers
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Herbal Medicine
Capsules:120 Capsules
41 In detail, the elevated extracellular ATP induced by SD stress stimulates P2× 7 R and down-regulates the expression of 5-HT 2B R by suppressing the activation of AKT, which inhibits the phosphorylation of FoxO3a and promotes its transportation into the nucleus, the reduced 5-HT 2B R alleviates the inhibition of STAT3 to cPLA 2 , the activated cPLA 2 further increases the release of AA and PGE2, these indicators have high relationship with the depressive-like behaviors, because in P2X 7 R knockout mice, the above changes of these indicators and behavioral performance are all eliminated
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