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Endoplasmic reticulum oxidoreductin (ERO) provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics | bioRxiv

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regenerative processes

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Additionally, several studies have demonstrated that Thal reduces the production of IL-6, TGF-β1, collagen type I and IV, α-SMA, vimentin, MMP-2 and -9, fibronectin and CTGF as well as to inhibit transdifferentiation, EMT and oxidative stress in TGF-β1-induced human and mouse lung fibroblasts (Tabata et al., 2007