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2.1 Age-related/inherited macular degeneration The RPE performs many crucial functions, such as phagocytosis, barrier, nutrient transportation, oxidative stress resistance, visual cycle maintenance and factors production, and is essential for the survival and function of the retina (Wang S

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Next, to screen the best PROTACs for TYR degradation, we performed western blot (WB) analysis to evaluate the degradation efficiency of TYR and the associated expression level of microphthalmia-associated transcription factor (MITF), a key transcriptional activator in melanin synthesis