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49 In bovine pulmonary arteries, hypoxia was shown to reduce cartilage oligomeric matrix protein expression in the ECM, decrease BMPR2 protein levels, downregulate SOD2 expression, increase reactive oxygen species (ROS), and inhibit the contractile phenotype of PASMCs

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Food-derived glutathione contents within tissues were estimated by subtracting endogenous glutathione-1- 13 C from the total glutathione-1- 13 C