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Glutathione is a delicate tripeptide, and vigorous shaking can break the protein bonds (denaturation) or create excessive air bubbles

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ICA, a metabolite with dual origins—derived both from gut microbial Trp catabolism and the breakdown of compounds in cruciferous vegetables (112, 160–163)—exemplifies ligand-specific modulation of the AhR and competitive interplay within critical immunometabolic pathways