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In 2011, dimeric integrin targeting PDCs were designed (Kimura et al., 2011), which featured ortho -carboranes as center and two cyclic c(RGDfK) peptides that were separately conjugated via a butanoic acid linker to each carbon atom in the cluster (Figure 10A)
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Its relevance centres on structured investigation of peptide mediated cellular processes, making it a useful compound for research environments requiring precise handling, documented study design, and clear scientific presentation
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