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Pretreatment of keratinocytes or cell lines (HaCaT cells) with the antioxidant compound N-acetylcysteine or the potent AHR antagonist naphthoflavone significantly inhibited the induction of CYP1B1 mRNA by ultraviolet B, and these data suggest that ultraviolet B photoproducts and AhR are involved in CYP1B1 induction (Ref

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