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Anchor logic: why the two are stacked Think of tissue repair as a construction project with two independent bottlenecks

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As a result, the actual rate of glucuronide excretion could either be lower (in efflux rate –limiting) or higher (in UGT rate-limiting) than the estimated rate of glucuronide excretion based on the cellular UGT activity (as measured from subcellular fraction) (Chen et al., 2003a