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Where drugs have systemic and local uses, for example, chloramphenicol, and the considerations around drug use are markedly different according to the route of administration, the monograph is split, as with earlier editions, into the relevant chapters
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For instance, DLBCL can be broadly classified into two major molecular subtypes: germinal center B-cell-like (GCB) and activated B-cell-like (ABC) DLBCL, each defined by distinct gene expression profiles and signaling pathway activation patterns [24]
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