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"Metallic taste is interesting, because we really don't know the biological basis for it," Nancy Rawson, vice president of the Monell Chemical Senses Center in Philadelphia, said

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Cooley and Su highlighted the role of HDAC inhibitors in acetylating MDM2, subsequently leading to the degradation of SS18::SSX thru the MULE ubiquitin ligase—thereby providing a histone-independent mechanism of action for HDAC inhibitors in SS [58]