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Assuming that K m for GSH is equal to K d (the dissociation constant of the complex GST-GSH) we can write the following equation: on the other hand, we express the dissociation free energy as the energy required to break the substrate-enzyme intermolecular interactions

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Furthermore, ALA can reverse ketamine-induced SZ-like symptoms in mice, potentially through its influence on BDNF in the PFC, as well as in a mouse model of depression (Vasconcelos et al., 2015