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Frontiers | The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia

Under glucose starvation conditions, damage to the pentose phosphate pathway can lead to a decrease in its metabolic product NADPH, resulting in a reduction in NADPH electron donors that prevent cystine from being converted to cysteine

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Avoid alcohol, excessive caffeine, smoking, and certain medications like high-dose paracetamol, chemotherapy drugs, and specific antibiotics