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An active ingredient is the substance responsible for the medicinal effects of a product specified by the substance's molecular structure or if the molecular structure is not known, defined by an unambiguous definition that identifies the substance

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Histopathologically, psoriasis is characterized by infiltration of immune cells, epidermal hyperproliferation, and abnormal keratinocyte (KC) differentiation ( Originally, psoriasis was thought to be due to dysregulation of keratinocyte proliferation ( S100 protein family The S100 protein family is a type of Ca 2+ -binding protein composed of a multigene family of low molecular mass proteins