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NRF2 activation decreases STING expression by destabilizing its mRNA, which leads to decreased type I IFN production, decreased antiviral cytosolic DNA sensing, and increased DNA virus infection in human cells, whereas the silencing of NRF2 decreases virus infectivity [133]

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Dose:100 mg

Reducing them through a mechanism with a favorable safety profile is the core rationale for longevity microdosing