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However, preclinical safety studies report no major toxicity across animal studies (mice, rats, rabbits, dogs) and showed no adverse effects across several organ systems
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GSH depletion at early stages of viral infection was also observed during the infection of VERO cells with clinically isolated herpes simplex type 1 virus, indicating a more general relationship between oxidative stress and viral replication [78]
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![Diseases with Documented Low Glutathione [70]](https://www.researchgate.net/publication/344547138/figure/fig3/AS:944431964364801@1602181535637/Diseases-with-Documented-Low-Glutathione-70.png)
