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ARINA-1 and Ascorbic Acid Stimulate CFTR-dependent Chloride Transport in WT CFBE41o − Cells but Not in HBE Cells On the basis of prior reports demonstrating a stimulatory effect of ascorbic acid on CFTR-mediated chloride transport (40, 41), we hypothesized that ARINA-1 may impact CFTR channel function to impart beneficial effects on MCT