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This suggests that neither ion-optics nor detector performance are the major limiting factors in the quest for increased sensitivity, but that the biological sample matrix impacts negatively on detection sensitivity, either through elevating the non-specific background signal, or through interferences that obscure analyte peaks, or through suppression of analyte ionisation

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Size:100 Grams (3.5 oz)

was also testified in HepG2 and HepaRG cells by culturing with 30 mM APAP ( via intrinsic and extrinsic pathways to prevent ALI in APAP-induced hepatotoxicity