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A review by Cardinali highlights melatonin’s potential in counteracting neurodegeneration and frailty in the elderly, noting melatonin’s excellent safety profile and low toxicity even at high doses (Cardinali, 2019)

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[DOI] [PubMed] [Google Scholar] 414.Venkatesh D., O'Brien N.A., Zandkarimi F., Tong D.R., Stokes M.E., Dunn D.E., Kengmana E.S., Aron A.T., Klein A.M., Csuka J.M., Moon S.H., Conrad M., Chang C.J., Lo D.C., D'Alessandro A., Prives C., Stockwell B.R