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In contrast, regulatory approval in Western countries remains limited: in the United States, glycyrrhizin is primarily recognized as a food sweetener rather than a therapeutic agent, while in Europe, its use is largely confined to traditional medicine and flavoring

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This complex mixture contains at least 18 active components, including active peptides, enzymes, amino acids, proteins, phospholipids, sugars, and other non-peptide elements ( Table 1 ) (54, 55)