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Glutathione depletion as a mechanism of Parkinson's disease: midlife depletion in animals induces symptoms and disability www.sciencedaily.com Depleting glutathione may cause Parkinson’s: Mice induced to have glutathione depletion as young adults did not develop Parkinsonian-like nerve damage and symptoms, while those who suffered from the depletion in late middle age did develop a loss of dopaminergic neurons specifically related to PD