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In addition, the cardiac structure was found to be altered by thyroid hormone deficiency in the form of lowered expression of sarcoplasmic reticulum Ca 2+ -ATPase and higher expression of phospholamban, which inhibited ATPase in the study of Klein and Danzi (2007)

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Joint pain and ligament injuries often result in inflammation and damage to the soft tissues, which can take a long time to heal without intervention