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At the molecular level, EMT is driven by alterations in key metabolic regulators, including transcription factors (TFs) Snail, Slug, and Twist that directly repress miR-200 family microRNAs, which normally target glycolytic genes GLUT1/3 and Pyruvate kinase M2 ( PKM2 ) [941,942]
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It must be supplied through food because the body cannot synthesise it
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