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However, our results on TΞ±1 potentiation of B reg differentiation in MS (Giacomini et al., 2017), together with its well-characterized pleiotropic activity able to shift inflammation toward a more anti-inflammatory milieu depending on the stimuli or pathological conditions (Romani et al., 2012, Giacomini et al., 2015) and its capacity to induce Treg generation and IL-10 production (Romani et al., 2006, Romani et al., 2017), indicate beneficial and advisable functions for a drug to be used in autoimmune diseases
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These mechanisms of action are primarily achieved by promoting the acetylation and nuclear translocation of NRF2, which in turn enhances the function of NRF2 in antioxidant and anti-inflammatory responses [67]
texture Helps to maintain skins natural moisture content and elasticity Maintains skins normal moisture levels youthful skin tone
