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During the resolution of inflammation, SPMs produced by polymorphonuclear cells and macrophages act to limit local tissue damage caused by inflammatory responses, including signaling cessation of polymorphonuclear cell infiltration, macrophage switching to an anti-inflammatory phenotype, apoptotic cell clearance, and reducing pain caused by nociceptor sensitization (61)
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SnapGene Viewer 5.1.4.1 was employed for DNA sequence handling and generation of plasmid maps (SnapGene software from Insightful Science
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