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Illustratively, in the mentioned laser-wound studies, human albumin solder supplemented with transforming growth factor (TGF)-β1 only, but not with HB-EGF or bFGF, increased the early postoperative strength of laser-welded wounds (Poppas et al., 1996), even though the superpulsed CO 2 laser enhanced fibroblast replication and appeared to stimulate bFGF and inhibit TGF-β1 secretion (Nowak et al., 2000)

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For instance, when excluding both supplements and medications, those with a deficient-low B 12 status had a significantly increased risk of incident depressive symptoms (OR 1·65 (95 % CI 1·07, 2·54)