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Simultaneously, dynamic monitoring of serum biomarkers, such as inflammatory cytokines, endothelial function indicators, and metabolic markers, may enable correlational analysis between therapeutic responses, biomarker fluctuations, and ED improvement
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Importantly, much of HDL’s (and apoA-I’s) inhibition of macrophage activation is mediated through altering cholesterol levels in plasma membrane lipid rafts through cholesterol efflux mediated by ABCG1/SR-BI and ABCA1
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