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Who Should Consult a Provider Before Proceeding Anyone on anticoagulants, anyone with a history of Leber’s disease (a hereditary optic neuropathy where cyanocobalamin is contraindicated), or anyone who is pregnant should walk through their full medical history with a provider before starting injections

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If the depressed oxygen consumption caused by NNMT overexpression indicates the depression of aerobic metabolism, the regulatory effect of NNMT on anaerobic metabolism might be reversed