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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Singh B, Schoeb TR, Bajpai P, Slominski A, Singh KK

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Consistent with a role of TGF-β as a brake on excessive CD8 + T cell function, TGF-β suppresses multiple effector functions of cytotoxic T cells, inhibiting expression of perforin, IFN-γ and granzymes A and B through SMADs in partnership with ATF1