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In the phase I trial NCT03725436 in patients with wild-type TP53 solid tumors, ALRN-6924 showed biological activity, and it is also being evaluated in phase II studies, including NCT04022876 in small-cell lung cancer and NCT02264613 in solid tumors and lymphomas

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oleifera to attenuate inflammation in streptozotocin-stimulated male Wister rats (Omodanisi et al