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VujkovicMde VriesJHLindemansJMacklonNSvander Spek PJSteegersEAet al

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Slopes in responders (61/75) were improved as follows, -7.4±9.7 to -0.9±2.9ml/min/1.73m 2 /year (P -10.0ml/min/1.73m 2 /y) (13/75) were remarkably improved from -18.9±16.4 to -1.4±3.5ml/min/1.73m 2 /year (P 45 ml/min and were on treatment with renin-angiotensin-aldosterone system (RAAS) inhibitors.Circulating Klotho (sKlotho) levels were measured using a validated immunoassay and Ao-PWV was determined by applanation tonometry (Sphygmocor system)