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During early injury response, proinflammatory macrophages, besides phagocytosing cellular debris and pathogens, elaborate cytokines [tumor necrosis factor (TNF), interleukin-1 (IL-1), and IL-6] as well as matrix metalloproteinases (MMPs) to drive acute inflammation and wound debridement (36)

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Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, Stadler MB et al