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NAD+ itself is the coenzyme that mitochondria burn through to make ATP and that sirtuins and DNA-repair enzymes consume as fuel
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While the exact mechanism that causes this increased infection rate of cells by both organisms remains unclear, future studies should explore how APOE ε 4 genotype cells as well as the APOEε4 protein are involved in the interaction between these microbes, and others such as HSV1, and host cells
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