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Recent studies have shown that intestinal flora can affect the cognitive function of AD patients through the “microbe-gut-brain” axis, and an imbalance of intestinal flora may lead to peripheral inflammation, inflammatory factors diffuse into the brain through the blood–brain barrier, which activates the neuroimmune response in the brain, and the excessive release of inflammatory factors causes neurotoxicity, which in turn leads to cognitive impairment (Chevalier et al., 2025)

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Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the… [PMID: 27349384] Laboratory literature summary: Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the need for nicotinamide-adenine dinucleotide (NAD)…