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Bibcode:2021RSOS....810382Z
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Unity Biotechnology has conducted Phase II trials of UBX0101 (a MDM2-p53 interaction inhibitor with a related mechanism) in osteoarthritis, with mixed results.[5] How the FDA ultimately approaches this drug class may shape the regulatory pathway for FOX04-DRI, but that's speculative at this point
It favors its accumulation in the regions of high electron flux in cells where reactive species are generated.
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