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doi: 10.1186/s12931-020-01609-4

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GPX1 is ubiquitously expressed in many tissues, mainly distributed in the liver, lungs, and kidneys, and plays a fundamental role in the regulation of intracellular ROS levels by reducing H 2 O 2 , lipid hydroperoxides (PLOOH), and peroxynitrite (ONOO − ) [104]