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In particular, prior torsion/detorsion studies have successfully administered antioxidant or cytoprotective agents in very small volumes or doses at the time of detorsion, demonstrating significant protection of testicular structure and function and establishing these parameters as acceptable in this model 22

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Thus, in a randomized clinical trial conducted in selenium-sufficient GD patients treated with methimazole, no beneficial effect of Se on the short-term control of thyroid hyperfunction was observed (82)