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liposomal glutathione randomized trial bioavailability outperforms plain glutathione in uptake, cell regeneration and systemic availability: evidence ...

R., Ramsden, C

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If the Cys to which HNE is bonded is located in a more hydrophobic region of the protein, the significant dipole moment of the aldehyde functionality of HNE will be a driving force to move that Cys closer to the surface of the protein, thereby exposing hydrophobic regions of the protein to the aqueous phase