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About 89.5% of those continuing tirzepatide maintained at least 80% of their lead-in weight loss versus 16.6% of those who switched to placebo

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This review systematically examines contemporary brain-targeted drug delivery strategies through three primary modalities: (1) molecular approaches including receptor-mediated transport, transporter-mediated uptake, tight junction modulation, adsorptive-mediated transcytosis, and CRISPR-enabled BBB penetration