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Cousin D, Zhang J, Hummersone MG, Matthews CS, Frigerio M, et al
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Tamoxifen increases the levels of ceramide, JNK phosphorylation and markers of apoptosis We next determined the effects of tamoxifen on caspase-3 activation, which is known to cleave poly (ADP-ribose) polymerase (PARP) and other proteins leading to apoptosis
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