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SS-31 vs MOTS-C: Quick Comparison Overview SS-31 vs MOTS-C: How SS-31 Works In the SS-31 vs MOTS-C comparison, SS-31’s mechanism is structural: the peptide (sequence: D-Arg-Dmt-Lys-Phe-NH2) selectively concentrates 1,000–5,000× within the inner mitochondrial membrane due to its alternating cationic and aromatic residues