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July 1, 2024
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These technical hurdles contribute to development costs exceeding $500 million per approved ADC, with 67% of clinical-stage candidates failing due to inadequate therapeutic indices ( 4.7 Target homogenization and market viability Current ADC development exhibits concerning target redundancy, with 43% of clinical candidates targeting HER2 or TROP2 ( Innovative engineering strategies are reshaping ADC development trajectories
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