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Considering the eating and drinking habits, the adaptive cytoprotection in the gastrointestinal tract starts in the upper parts, in the stomach and duodenum, and may beneficially affect other parts (and thereby, adaptive cytoprotection occurs between stomach → stomach

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2.3 Neurooxidative stress and cognitive dysfunction in diabetes The brain is the most oxygen-consuming organ in the human body, with the normal human brain accounting for more than 20 to 30 percent of the body’s total oxygen consumption, but the brain is low in antioxidants, making it more susceptible to the effects of oxidative stress (39)