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Neither cause significant visual loss.[1] KF rings occur in 66% of cases, more often in those with neurological than with liver problems.[18] Kidneys: renal tubular acidosis, a disorder of bicarbonate handling by the proximal tubules leads to nephrocalcinosis (calcium accumulation in the kidneys), weakening of the bone (due to calcium and phosphate loss) and occasionally aminoaciduria (loss of amino acids, needed for protein synthesis).[1] Heart: cardiomyopathy (weakness of the heart muscle) is a rare but recognized problem in Wilson’s disease
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